K2 (MK-7)
Vitamin K2 (MK-7) is a fat-soluble vitamin that plays a crucial role in bone and cardiovascular health. It is a subtype of vitamin K2, known as menaquinone-7, which is produced by bacterial fermentation.
Effectiveness and Risk Overview
Condition | Effectiveness | Details |
|---|---|---|
| Osteoporosis | MK-7 supplementation has been associated with improved bone mineral density and reduced risk of osteoporotic fractures, particularly in older adults and postmenopausal women, by enhancing bone mineralization. | |
| Cardiovascular Health | By preventing arterial calcification and supporting vascular health, K2 (MK-7) contributes to overall cardiovascular health. Research indicates a reduction in cardiovascular events and mortality with adequate MK-7 intake. | |
| Bone Health | MK-7, a form of Vitamin K2, is crucial for bone health as it helps in the activation of osteocalcin, a protein necessary for bone mineralization. Studies have demonstrated that MK-7 supplementation can improve bone density and reduce the risk of fractures. | |
| Artery Calcification/Atherosclerosis | K2 (MK-7) has been shown to inhibit the progression of arterial calcification and reduce the risk of cardiovascular disease by activating matrix Gla protein (MGP), a potent inhibitor of arterial calcification. Clinical trials and observational studies support its beneficial effects on cardiovascular health. | |
| May interact with blood thinners. | Vitamin K2 (MK-7) can counteract the effects of anticoagulant medications, such as warfarin, by promoting blood clotting, which can lead to increased risk of thrombosis. |