5-MTHF L-Methylfolate

5-MTHF L-Methylfolate (also sometimes called Levomefolate) is the active form of folate – also known as vitamin B9. It's used by the body to perform a variety of critical functions, including synthesizing DNA, repairing and methylating DNA, and serving as a cofactor in biological reactions, particularly in the nervous system.

Effectiveness and Risk Overview

Condition
Effectiveness
Details
May mask B12 deficiency symptoms.
Taking 5-MTHF without adequate vitamin B12 can mask the symptoms of a B12 deficiency, potentially leading to untreated neurological damage.
Interferes with certain anticonvulsants efficacy.
High doses of folate, including 5-MTHF, may interfere with the efficacy of certain anticonvulsant medications, potentially leading to reduced seizure control.

Related Studies

Best 5-MTHF L-Methylfolate Combinations for Maximum Benefits