Great Synergy!
4

Can you take Adenosyl B12 and Alpha Ketoglutarate together?

Interaction Details

Taking Adenosyl B12 and Alpha Ketoglutarate together has the potential for good synergy, suggesting a rating of 4 out of 5.

The combination of Adenosyl B12 and Alpha Ketoglutarate (AKG) may exhibit a synergistic effect due to their roles in energy production and metabolism. Adenosyl B12 is a form of Vitamin B12 crucial for the synthesis of methionine and S-adenosylmethionine (SAMe), involved in methylation processes and neurotransmitter synthesis. It also plays a significant role in the production of energy from food. Alpha Ketoglutarate is an intermediate in the Krebs cycle (also known as the citric acid cycle or TCA cycle), which is pivotal for cellular energy production. AKG can enhance the metabolism of nutrients and support the production of ATP, the primary energy currency of the cell. The synergy arises because efficient energy production and metabolic processes are interlinked; optimal levels of one can support the effectiveness of the other. Adenosyl B12 ensures proper metabolic function, including in pathways related to energy production where AKG is a key player. This complementary action can enhance overall energy production and metabolic efficiency, potentially leading to improved physical and mental performance.

Potential Benefits

Enhances energy production efficiently.
The combination of Adenosyl B12 and Alpha Ketoglutarate supports the Krebs cycle, a crucial process for energy production in cells, thereby enhancing overall energy levels.
Supports detoxification processes strongly.
Adenosyl B12 plays a role in the metabolism and detoxification processes, and when combined with Alpha Ketoglutarate, it may support the body's ability to detoxify more effectively.
Boosts mental clarity and focus.
The synergy between Adenosyl B12 and Alpha Ketoglutarate may contribute to improved mental functions, including clarity and focus, by supporting the health of neurons and the efficiency of energy production in the brain.

Potential Risks

May cause gastrointestinal disturbances.
Some studies suggest that the combination of certain supplements can lead to gastrointestinal side effects due to their synergistic effects on metabolic pathways and potentially irritating the stomach lining.

Adenosyl B12

Adenosyl B12, also known as AdoB12 or Dibencozide, is a form of vitamin B12 that plays a crucial role in energy production and can be found in some dietary supplements.

Alpha Ketoglutarate

Alpha Ketoglutarate (AKG) is a key intermediate in the Krebs cycle, playing a crucial role in cellular energy production and amino acid metabolism. It is an amino acid derivative that can be found in various foods, but supplementing with AKG can have several benefits, including: