Great Synergy!

Can you take Adenosine Triphosphate and Alpha Ketoglutarate together?

Interaction Details

Taking Adenosine Triphosphate (ATP) and Alpha Ketoglutarate (α-KG) together has the potential for good synergy, suggesting a rating of 4 out of 5.

ATP and α-KG interact synergistically through their roles in cellular energy production and metabolism. ATP is a direct energy source for cellular functions, while α-KG is a key intermediate in the Krebs cycle, which generates energy for the cell. α-KG can increase the production of ATP by enhancing the efficiency of the Krebs cycle and subsequently the electron transport chain. Conversely, supplementation with ATP can potentially increase the utilization and recycling of α-KG by providing the necessary energy for its conversion into other metabolites. This interplay can enhance the overall energy production and metabolic efficiency of the cell. Furthermore, both compounds are involved in various anabolic processes; their combined effect could potentially amplify their individual benefits on exercise performance, recovery, and cellular health.

Potential Benefits

Increases energy production rapidly.
The combination of Adenosine Triphosphate (ATP) and Alpha Ketoglutarate (AKG) can enhance energy production in cells. ATP is a direct energy source for cells, while AKG is a key intermediate in the Krebs cycle, which generates energy. Together, they can rapidly increase energy production, supporting physical performance and reducing fatigue.

Enhances muscle recovery quickly.
ATP and AKG can help promote muscle recovery after exercise. ATP provides energy for muscle contractions and relaxations, while AKG can help reduce muscle damage and inflammation. The combination of both supplements can quickly enhance muscle recovery, reducing muscle soreness and improving exercise performance.

Supports cellular health strongly.
The combination of ATP and AKG can support cellular health by promoting energy production, reducing oxidative stress, and enhancing cellular cleaning processes. AKG can help maintain the health of mitochondria, the energy-producing structures within cells, while ATP provides energy for cellular processes.

Potential Risks

Causes kidney stone formation.
There is evidence that high levels of ATP and AKG can increase the risk of kidney stone formation when taken together. AKG can increase the levels of oxalate, a compound that can form kidney stones, while ATP can increase the levels of calcium, which can also contribute to kidney stone formation.

Disrupts normal gut bacteria.
The combination of ATP and AKG can alter the gut microbiome, leading to changes in the normal balance of gut bacteria. This can cause digestive issues, such as bloating, gas, and diarrhea.

Recommended Supplement for antioxidants

Related Studies

Adenosine Triphosphate

Adenosine Triphosphate (ATP) is a molecule that serves as the primary energy carrier in cells, playing a crucial role in various cellular processes, including muscle contraction, nerve impulse transmission, and biosynthesis.

Alpha Ketoglutarate

Alpha Ketoglutarate (AKG) is a key intermediate in the Krebs cycle, playing a crucial role in cellular energy production and amino acid metabolism. It is an amino acid derivative that can be found in various foods, but supplementing with AKG can have several benefits, including: