Can you take Arginine and Citrulline together?

Taking Arginine and Citrulline together has a high potential for synergy as both are involved in the nitric oxide cycle, enhancing vasodilation and blood flow, suggesting a rating of 5 out of 5.

Both Arginine and Citrulline play crucial roles in the production of nitric oxide (NO), a key molecule for vascular health. Citrulline is more efficient at increasing arginine levels and subsequently NO production because it bypasses some of the metabolic limitations associated with arginine supplementation. When taken together, they potentially create a synergistic effect by maximizing NO production pathways. Citrulline supplementation can increase arginine levels, thereby potentially enhancing the effects typically associated with arginine supplementation alone. The combination may lead to improved vasodilation, enhanced exercise performance, and better overall cardiovascular health.