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Can you take Aged Garlic Extract and Alpha Ketoglutarate together?

Interaction Details

Taking Aged Garlic Extract and Alpha Ketoglutarate together has the potential for good synergy, suggesting a rating of 4 out of 5.

The combination of Aged Garlic Extract and Alpha Ketoglutarate may exhibit synergistic effects through their complementary mechanisms of action. Aged Garlic Extract is known for its cardiovascular benefits, including antioxidant and anti-inflammatory properties, while Alpha Ketoglutarate (AKG) plays a role in cellular energy production and has been shown to have antioxidant effects as well. AKG can support the TCA cycle, enhancing energy production and potentially increasing the utilization of nutrients. Meanwhile, the active compounds in Aged Garlic Extract, such as S-allyl cysteine, can help protect against oxidative stress and inflammation. The combination could enhance the antioxidant capacity, potentially leading to increased protection against cardiovascular diseases and improved overall cellular health. The synergistic effect might be attributed to the comprehensive coverage of pathways involved in oxidative stress and energy production, suggesting that together, they could offer a more robust protective and energizing effect than either supplement alone.

Potential Benefits

Enhances cardiovascular health strongly.
The combination of Aged Garlic Extract and Alpha Ketoglutarate may help to improve cardiovascular health by reducing blood pressure, improving blood lipid profiles, and preventing platelet aggregation, ultimately leading to a reduced risk of heart disease.
Boosts immune system function.
The synergy between Aged Garlic Extract and Alpha Ketoglutarate may help to stimulate the immune system, increasing the production of antibodies and activating immune cells, such as macrophages and T-cells, to fight off infections and diseases.
Increases antioxidant defenses.
The combination of Aged Garlic Extract and Alpha Ketoglutarate may help to increase the body's antioxidant defenses by reducing oxidative stress and inflammation, and promoting the production of antioxidants, such as glutathione, to protect against cell damage and disease.

Potential Risks

Causes kidney stone formation.
The combination of Aged Garlic Extract and Alpha Ketoglutarate may increase the risk of kidney stone formation due to the potential for increased oxalate levels, which can combine with calcium to form kidney stones.
Triggers respiratory acidosis.
The interaction between Aged Garlic Extract and Alpha Ketoglutarate may lead to an increased risk of respiratory acidosis, a condition characterized by an excessive buildup of acidic compounds in the body, which can be life-threatening if left untreated.
Recommended Supplement for antioxidants

Recommended Supplement for antioxidants

Aged Garlic Extract

Aged Garlic Extract is a dietary supplement made from garlic that has been aged for several months, resulting in a odorless and gentle product. It is rich in antioxidants and has been shown to have various health benefits.

Alpha Ketoglutarate

Alpha Ketoglutarate (AKG) is a key intermediate in the Krebs cycle, playing a crucial role in cellular energy production and amino acid metabolism. It is an amino acid derivative that can be found in various foods, but supplementing with AKG can have several benefits, including: