Can you take Citrulline and L-Citrulline together?

Taking Citrulline and L-Citrulline together essentially means taking the same supplement, as they are often used interchangeably, with L-Citrulline being the specific form of Citrulline that is commonly used, suggesting a rating of 5 out of 5.

The primary reason for this high synergy rating is that Citrulline and L-Citrulline are essentially the same in terms of their biochemical role. L-Citrulline is simply Citrulline in its L-form, which is the form that is biologically active and commonly used in supplements. Therefore, taking them together doesn't provide a synergistic effect in the sense of combining two different substances but rather is redundant. Both are used to increase arginine levels, improve nitric oxide production, and enhance blood flow. The body utilizes L-Citrulline effectively, and additional Citrulline (if not specifically in the L-form) is either already in the L-form or not utilized as effectively. The redundancy suggests a high level of 'synergy' in terms of intended effect, albeit not a combination of different mechanisms.