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Can you take Alpha Lipoic Acid and R-lipoic acid together?

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Taking Alpha Lipoic Acid and R-lipoic acid together has the potential for great synergy, suggesting a rating of 5 out of 5.

Alpha Lipoic Acid and R-lipoic acid are both forms of lipoic acid, a compound involved in energy metabolism and antioxidant defenses. The R-form is the biologically active form, while Alpha Lipoic Acid is a racemic mixture containing both R- and S-lipoic acid. When taken together, R-lipoic acid can enhance the bioavailability and efficacy of Alpha Lipoic Acid by ensuring a higher proportion of the active R-form. This can lead to increased antioxidant activity, improved mitochondrial function, and enhanced glucose metabolism. The combination may also have a synergistic effect on reducing oxidative stress and inflammation, as the R-lipoic acid can amplify the benefits of Alpha Lipoic Acid. Overall, the combination of Alpha Lipoic Acid and R-lipoic acid can create a comprehensive antioxidant and metabolic support system.

Potential Benefits

Antioxidant power increased.
The combination of Alpha Lipoic Acid and R-lipoic acid has been shown to increase antioxidant power, as R-lipoic acid is more easily absorbed by the body and can regenerate Alpha Lipoic Acid, creating a synergistic effect that enhances the overall antioxidant capacity.
Cell protection enhanced.
The synergy between Alpha Lipoic Acid and R-lipoic acid provides enhanced protection against cell damage, as they work together to neutralize free radicals and promote cellular health, reducing the risk of chronic diseases such as cancer and neurodegenerative disorders.
Energy production boosted.
The combination of Alpha Lipoic Acid and R-lipoic acid has been found to boost energy production in cells, as they play a crucial role in the metabolism of carbohydrates, fats, and proteins, and their synergistic effect can enhance the production of ATP, the primary energy currency of the cell.

Potential Risks

Thyroid issues exacerbated.
Some studies have suggested that the combination of Alpha Lipoic Acid and R-lipoic acid may exacerbate thyroid issues, particularly in individuals with hypothyroidism, as the synergistic effect of the two supplements may interfere with thyroid hormone production or regulation, although more research is needed to confirm this risk.
Recommended Supplement for antioxidants

Recommended Supplement for antioxidants

Related Studies

Alpha Lipoic Acid

Alpha Lipoic Acid is an antioxidant found in every cell of the body, playing a crucial role in energy production and can be taken as a dietary supplement. It has been found to have various benefits, including:

R-lipoic acid

R-lipoic acid is a potent antioxidant supplement, an isomer of alpha-lipoic acid, with potentially better bioavailability. It plays a role in energy production and can help protect against cell damage.