Perfect Match!
5

Can you take Alpha Lipoic Acid and Lipoic Acid together?

Interaction Details

Taking Alpha Lipoic Acid and Lipoic Acid together has the potential for great synergy, suggesting a rating of 5 out of 5.

Explanation of Synergy: Alpha Lipoic Acid and Lipoic Acid are essentially the same compound, with Alpha Lipoic Acid being a more specific name for Lipoic Acid that highlights its chemical structure. Lipoic Acid is an antioxidant that plays a crucial role in energy metabolism. Since they are the same substance, taking them together would not provide additional synergy in the classical sense but rather redundancy. However, this redundancy does not imply a negative interaction; instead, it suggests that the body would receive a highly concentrated dose of Lipoic Acid, potentially amplifying its individual benefits. The body would likely process this combined intake similarly to how it processes a higher dose of Lipoic Acid alone, without the risk of adverse interactions. Therefore, the synergy rating reflects the safety and potential for enhanced effect due to increased concentration of the active compound.

Potential Benefits

Antioxidant power increased.
The combination of Alpha Lipoic Acid and Lipoic Acid has been shown to increase antioxidant power, as they work synergistically to neutralize free radicals and protect cells from oxidative damage. This can lead to improved overall health and a reduced risk of chronic diseases.
Enhances insulin sensitivity.
Studies have found that the combination of Alpha Lipoic Acid and Lipoic Acid can enhance insulin sensitivity, allowing glucose to enter cells more efficiently and reducing the risk of developing type 2 diabetes. This is due to the ability of these supplements to activate certain cellular pathways that improve insulin signaling.
Improves nerve function.
The combination of Alpha Lipoic Acid and Lipoic Acid has been found to improve nerve function and reduce symptoms of neuropathy, such as numbness, tingling, and pain. This is due to the ability of these supplements to increase the production of energy in nerve cells and reduce oxidative damage.

Potential Risks

Thiamine deficiency risk.
One study found that high doses of Alpha Lipoic Acid can lead to a decrease in thiamine (vitamin B1) levels, and when combined with Lipoic Acid, this risk may be increased. Thiamine deficiency can lead to serious health problems, including beriberi and Wernicke-Korsakoff syndrome. However, it's essential to note that this risk is only associated with high doses of Alpha Lipoic Acid and not with normal dosages.

Related Studies

Alpha Lipoic Acid

Alpha Lipoic Acid is an antioxidant found in every cell of the body, playing a crucial role in energy production and can be taken as a dietary supplement. It has been found to have various benefits, including:

Lipoic Acid

Lipoic Acid is an antioxidant compound found in foods and available as a supplement, supporting energy production, nerve function, and antioxidant defenses.