Vitamin K2 MK-4
Vitamin K2 MK-4 is a subtype of vitamin K2, a fat-soluble vitamin necessary for blood clotting and bone health. It is one of the two main forms of vitamin K2, the other being MK-7.
Effectiveness and Risk Overview
Condition | Effectiveness | Details |
|---|---|---|
| Osteoporosis | Vitamin K2 MK-4 has been shown to improve bone mineral density and reduce the risk of osteoporotic fractures by enhancing osteocalcin carboxylation and bone mineralization. | |
| Cardiovascular Health | By reducing arterial calcification and improving blood vessel elasticity, Vitamin K2 MK-4 contributes to overall cardiovascular health. It has been associated with a lower risk of cardiovascular events in various studies. | |
| Bone Health | Vitamin K2 MK-4 is known to play a crucial role in bone health by promoting the carboxylation of osteocalcin, which is essential for bone mineralization. Studies have shown that it can improve bone density and reduce the risk of fractures. | |
| Arterial Calcification/Atherosclerosis | Vitamin K2 MK-4 has been shown to inhibit arterial calcification by activating matrix Gla protein (MGP), a potent inhibitor of calcification. Clinical studies have demonstrated its effectiveness in reducing arterial stiffness and calcification. | |
| May interact with anticoagulants badly. | Vitamin K2 MK-4 can counteract the effects of anticoagulant medications such as warfarin, potentially leading to an increased risk of thrombosis. |